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PAI-1 genetic polymorphisms influence septic patients' outcomes by regulating neutrophil activity

BACKGROUND: Plasminogen activator inhibitor-1 (PAI-1) plays an important role in the pathophysiology of sepsis, but the exact mechanism remains debatable. In this study, we investigated the associations among the serum levels of PAI-1, the incidence of 4G/5G promoter PAI-1 gene polymorphisms, immuno...

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Detalles Bibliográficos
Autores principales:	Jiang, Shaowei, Wang, Yang, Chen, Liang, Mu, Honghua, Meaney, Connor, Fan, Yiwen, Pillay, Janesh, Wang, Hairong, Zhang, Jincheng, Pan, Shuming, Gao, Chengjin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2023
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10431590/ https://www.ncbi.nlm.nih.gov/pubmed/37439338 http://dx.doi.org/10.1097/CM9.0000000000002316

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