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The σ(B) alternative sigma factor circuit modulates noise to generate different types of pulsing dynamics
Single-cell approaches are revealing a high degree of heterogeneity, or noise, in gene expression in isogenic bacteria. How gene circuits modulate this noise in gene expression to generate robust output dynamics is unclear. Here we use the Bacillus subtilis alternative sigma factor σ(B) as a model s...
Autores principales: | Loman, Torkel E., Locke, James C. W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10431680/ https://www.ncbi.nlm.nih.gov/pubmed/37540712 http://dx.doi.org/10.1371/journal.pcbi.1011265 |
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