A physiologically based pharmacokinetic model to optimize the dosage regimen and withdrawal time of cefquinome in pigs

Cefquinome is widely used to treat respiratory tract diseases of swine. While extra-label dosages of cefquinome could improve clinical efficacy, they might lead to excessively high residues in animal-derived food. In this study, a physiologically based pharmacokinetic (PBPK) model was calibrated bas...

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Detalles Bibliográficos
Autores principales: Mi, Kun, Sun, Lei, Hou, Yixuan, Cai, Xin, Zhou, Kaixiang, Ma, Wenjin, Xu, Xiangyue, Pan, Yuanhu, Liu, Zhenli, Huang, Lingli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10431683/
https://www.ncbi.nlm.nih.gov/pubmed/37585381
http://dx.doi.org/10.1371/journal.pcbi.1011331

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10431683/
https://www.ncbi.nlm.nih.gov/pubmed/37585381
http://dx.doi.org/10.1371/journal.pcbi.1011331

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