Cargando…

A physiologically based pharmacokinetic model to optimize the dosage regimen and withdrawal time of cefquinome in pigs

Cefquinome is widely used to treat respiratory tract diseases of swine. While extra-label dosages of cefquinome could improve clinical efficacy, they might lead to excessively high residues in animal-derived food. In this study, a physiologically based pharmacokinetic (PBPK) model was calibrated bas...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mi, Kun, Sun, Lei, Hou, Yixuan, Cai, Xin, Zhou, Kaixiang, Ma, Wenjin, Xu, Xiangyue, Pan, Yuanhu, Liu, Zhenli, Huang, Lingli
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10431683/ https://www.ncbi.nlm.nih.gov/pubmed/37585381 http://dx.doi.org/10.1371/journal.pcbi.1011331

Ejemplares similares

Determination of Susceptibility Breakpoint for Cefquinome against Streptococcus suis in Pigs
por: Mi, Kun, et al.
Publicado: (2021)

Optimization and Validation of Dosage Regimen for Ceftiofur against Pasteurella multocida in Swine by Physiological Based Pharmacokinetic–Pharmacodynamic Model
por: Mi, Kun, et al.
Publicado: (2022)

Application of Semi-Mechanistic Pharmacokinetic and Pharmacodynamic Model in Antimicrobial Resistance
por: Mi, Kun, et al.
Publicado: (2022)

Apply a Physiologically Based Pharmacokinetic Model to Promote the Development of Enrofloxacin Granules: Predict Withdrawal Interval and Toxicity Dose
por: Zhou, Kaixiang, et al.
Publicado: (2021)

Evidence for Establishing the Clinical Breakpoint of Cefquinome against Haemophilus Parasuis in China
por: Mi, Kun, et al.
Publicado: (2021)

Application of a Physiologically Based Pharmacokinetic Model to Develop a Veterinary Amorphous Enrofloxacin Solid Dispersion
por: Zhou, Kaixiang, et al.
Publicado: (2021)

Metabolite Identification and Pharmacokinetic Behavior of Diaveridine in the Plasma of Pigs and Chickens Based on Radioactive Tracing Coupled With LC/MS-IT-TOF Assay
por: Wang, Liye, et al.
Publicado: (2022)

Pharmacokinetic and pharmacodynamic integration for optimal dosage of cefquinome against Streptococcus equi subsp. equi in foals
por: Lee, Dong-Ha, et al.
Publicado: (2020)

Excretion and Residual Concentration Correlations of Salbutamol Between Edible Tissues and Living Samples in Pigs and Goats
por: Sun, Lei, et al.
Publicado: (2021)

Ex Vivo Pharmacokinetics and Pharmacodynamics Modeling and Optimal Regimens Evaluation of Cefquinome Against Bovine Mastitis Caused by Staphylococcus aureus
por: Jiang, Li-jie, et al.
Publicado: (2022)

Preparation of Cefquinome Sulfate Proliposome and its Pharmacokinetics in Rabbit
por: FU, Qiang, et al.
Publicado: (2013)

Preparation of Aditoprim Injection against Streptococcus suis in Pigs and a Dose Regimen Based on Pharmacokinetic-Pharmacodynamic Modeling
por: Qu, Wei, et al.
Publicado: (2022)

Formulation of a rational dosage regimen of ceftiofur hydrochloride oily suspension by pharmacokinetic-pharmacodynamic (PK-PD) model for treatment of swine Streptococcus suis infection
por: Luo, Wanhe, et al.
Publicado: (2021)

Salmonella antimicrobials inherited and the non-inherited resistance: mechanisms and alternative therapeutic strategies
por: Zhou, Kaixiang, et al.
Publicado: (2023)

Pharmacokinetic and Pharmacodynamic Drug–Drug Interactions: Research Methods and Applications
por: Sun, Lei, et al.
Publicado: (2023)

The Application of Hollow Fiber Cartridge in Biomedicine
por: Hou, Yixuan, et al.
Publicado: (2022)

The pharmacokinetics and pharmacodynamics of cefquinome against Streptococcus agalactiae in a murine mastitis model
por: Yang, Qingwen, et al.
Publicado: (2023)

Dose Assessment of Cefquinome by Pharmacokinetic/Pharmacodynamic Modeling in Mouse Model of Staphylococcus aureus Mastitis
por: Yu, Yang, et al.
Publicado: (2016)

Murine Thigh Microdialysis to Evaluate the Pharmacokinetic/Pharmacodynamic Integration of Cefquinome Against Actinobacillus pleuropneumoniae
por: Zhang, Longfei, et al.
Publicado: (2020)

Cefquinome shows a higher impact on the pig gut microbiome and resistome compared to ceftiofur
por: Rutjens, Sofie, et al.
Publicado: (2023)

Integration of PK/PD for dose optimization of Cefquinome against Staphylococcus aureus causing septicemia in cattle
por: Ahmad, Ijaz, et al.
Publicado: (2015)

Comparative Pharmacokinetics of Cefquinome (Cobactan 2.5%) following Repeated Intramuscular Administrations in Sheep and Goats
por: El-Hewaity, Mohamed, et al.
Publicado: (2014)

Pharmacokinetics, bioavailability and dose assessment of Cefquinome against Escherichia coli in black swans (Cygnus atratus)
por: Zhao, Dong-Hao, et al.
Publicado: (2017)

PK-PD Modeling and Optimal Dosing Regimen of Acetylkitasamycin against Streptococcus suis in Piglets
por: Huang, Anxiong, et al.
Publicado: (2022)

Preparation, characterization and pharmacokinetics of cyadox nanosuspension
por: Sattar, Adeel, et al.
Publicado: (2017)

Exposure to benzylpenicillin after different dosage regimens in growing pigs
por: Sjölund, Marie, et al.
Publicado: (2020)

Attenuation of Withdrawal Signs, Blood Cortisol, and Glucose Level with Various Dosage Regimens of Morphine after Precipitated Withdrawal Syndrome in Mice
por: Motaghinejad, Majid, et al.
Publicado: (2016)

Optimal Regimens and Clinical Breakpoint of Avilamycin Against Clostridium perfringens in Swine Based on PK-PD Study
por: Huang, Anxiong, et al.
Publicado: (2022)

Development of Stability-Indicating Methods for Cefquinome Sulphate
por: Shantier, Shaza W., et al.
Publicado: (2013)

In Vivo Pharmacokinetics/Pharmacodynamics of Cefquinome in an Experimental Mouse Model of Staphylococcus Aureus Mastitis following Intramammary Infusion
por: Yu, Yang, et al.
Publicado: (2016)

Pharmacokinetic/Pharmacodynamic Correlation of Cefquinome Against Experimental Catheter-Associated Biofilm Infection Due to Staphylococcus aureus
por: Zhou, Yu-Feng, et al.
Publicado: (2016)

Microdialysis Determination of Cefquinome Pharmacokinetics in Murine Thigh From Healthy, Neutropenic, and Actinobacillus pleuropneumoniae-Infected Mice
por: Zhang, Longfei, et al.
Publicado: (2019)

Subcutaneous pharmacokinetics and dosage regimen of cefotaxime in buffalo calves (Bubalus bubalis)
por: Sharma, Suresh Kumar, et al.
Publicado: (2006)

Population Pharmacokinetic Modeling of Zaltoprofen in Healthy Adults: Exploring the Dosage Regimen
por: Jang, Ji-Hun, et al.
Publicado: (2023)

Intestinal Exposure to Ceftiofur and Cefquinome after Intramuscular Treatment and the Impact of Ceftiofur on the Pig Fecal Microbiome and Resistome
por: Rutjens, Sofie, et al.
Publicado: (2022)

Pharmacokinetic and pharmacodynamic modeling of cyadox against Clostridium perfringens in swine
por: Yan, Lei, et al.
Publicado: (2017)

Disposition and Residue Depletion of Metronidazole in Pigs and Broilers
por: Pan, Yuanhu, et al.
Publicado: (2017)

In vitro dynamic pharmacokinetic/pharmacodynamic(PK/PD) modeling and PK/PD cutoff of cefquinome against Haemophilus parasuis
por: Xiao, Xia, et al.
Publicado: (2015)

Efficacy of Cefquinome against Escherichia coli Environmental Mastitis Assessed by Pharmacokinetic and Pharmacodynamic Integration in Lactating Mouse Model
por: Yu, Yang, et al.
Publicado: (2017)

Stability of Ceftiofur Sodium and Cefquinome Sulphate in Intravenous Solutions
por: Dołhań, Agnieszka, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_kn67psmq473et3f5omdnn0ubun