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Neurological Effects of Combining Low Toxic Dose of Tramadol and Nicotine: An Animal Model Evidence of Endoplasmic Reticulum Stress

Tramadol abuse is a common problem in the Middle East in conjunction with smoking. The current study applied immunohistochemistry, western blot, real-time PCR, and ELISA to test the combination toxicity. Low toxic doses of tramadol induced animal brain cortex inflammation and hippocampus injury. Add...

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Detalles Bibliográficos
Autores principales: Ghorab, Doaa, Abu-El-Rub, Ejlal M., Gharaibeh, Mohamed Hamdi, Yehya, Alaa, Khasawneh, Ramada R., Matalqah, Laila M., Helaly, Ahmed Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10432102/
https://www.ncbi.nlm.nih.gov/pubmed/37593523
http://dx.doi.org/10.1155/2023/1953356