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Neurological Effects of Combining Low Toxic Dose of Tramadol and Nicotine: An Animal Model Evidence of Endoplasmic Reticulum Stress
Tramadol abuse is a common problem in the Middle East in conjunction with smoking. The current study applied immunohistochemistry, western blot, real-time PCR, and ELISA to test the combination toxicity. Low toxic doses of tramadol induced animal brain cortex inflammation and hippocampus injury. Add...
Autores principales: | Ghorab, Doaa, Abu-El-Rub, Ejlal M., Gharaibeh, Mohamed Hamdi, Yehya, Alaa, Khasawneh, Ramada R., Matalqah, Laila M., Helaly, Ahmed Mohamed |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10432102/ https://www.ncbi.nlm.nih.gov/pubmed/37593523 http://dx.doi.org/10.1155/2023/1953356 |
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