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Oxidant-modified amylin fibrils and aggregates alter the inflammatory profile of multiple myeloid cell types, but are non-toxic to islet β cells

Diabetes mellitus currently affects ∼10% of the population worldwide, with Type 2 predominating, and this incidence is increasing steadily. Both Type 1 and 2 are complex diseases, involving β-cell death and chronic inflammation, but the pathways involved are unresolved. Chronic inflammation is chara...

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Detalles Bibliográficos
Autores principales: Clemen, Ramona, Fuentes-Lemus, Eduardo, Bekeschus, Sander, Davies, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10432244/
https://www.ncbi.nlm.nih.gov/pubmed/37544243
http://dx.doi.org/10.1016/j.redox.2023.102835

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