Cargando…
The mechanistic role of cardiac glycosides in DNA damage response and repair signaling
Cardiac glycosides (CGs) are a class of bioactive organic compounds well-known for their application in treating heart disease despite a narrow therapeutic window. Considerable evidence has demonstrated the potential to repurpose CGs for cancer treatment. Chemical modification of these CGs has been...
Autores principales: | Ainembabazi, Diana, Zhang, Youwei, Turchi, John J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10432338/ https://www.ncbi.nlm.nih.gov/pubmed/37584722 http://dx.doi.org/10.1007/s00018-023-04910-9 |
Ejemplares similares
-
Synthesis and Biological Evaluation of Cardiac Glycosides for Cancer Therapy by Targeting the DNA Damage Response
por: Ainembabazi, Diana, et al.
Publicado: (2022) -
Chemotherapy induced DNA damage response: Convergence of drugs and pathways
por: Woods, Derek, et al.
Publicado: (2013) -
Editorial: Targeting DNA repair and the DNA damage response: Beyond the standard PI3 kinase-like kinases
por: Turchi, John J., et al.
Publicado: (2022) -
The Role of Circular RNAs in DNA Damage Response and Repair
por: Papaspyropoulos, Angelos, et al.
Publicado: (2021) -
The Cardiac Glycosides
por: Barbour, H. G.
Publicado: (1937)