Cargando…
AMBRA1 phosphorylation by CDK1 and PLK1 regulates mitotic spindle orientation
AMBRA1 is a crucial factor for nervous system development, and its function has been mainly associated with autophagy. It has been also linked to cell proliferation control, through its ability to regulate c-Myc and D-type cyclins protein levels, thus regulating G1-S transition. However, it remains...
Autores principales: | Faienza, Fiorella, Polverino, Federica, Rajendraprasad, Girish, Milletti, Giacomo, Hu, Zehan, Colella, Barbara, Gargano, Deborah, Strappazzon, Flavie, Rizza, Salvatore, Vistesen, Mette Vixø, Luo, Yonglun, Antonioli, Manuela, Cianfanelli, Valentina, Ferraina, Caterina, Fimia, Gian Maria, Filomeni, Giuseppe, De Zio, Daniela, Dengjel, Joern, Barisic, Marin, Guarguaglini, Giulia, Di Bartolomeo, Sabrina, Cecconi, Francesco |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10432340/ https://www.ncbi.nlm.nih.gov/pubmed/37584777 http://dx.doi.org/10.1007/s00018-023-04878-6 |
Ejemplares similares
-
Prosurvival AMBRA1 turns into a proapoptotic BH3-like protein during mitochondrial apoptosis
por: Strappazzon, Flavie, et al.
Publicado: (2016) -
The Cancermuts software package for the prioritization of missense cancer variants: a case study of AMBRA1 in melanoma
por: Tiberti, Matteo, et al.
Publicado: (2022) -
AMBRA1-induced mitophagy: A new mechanism to cope with cancer?
por: Strappazzon, Flavie, et al.
Publicado: (2015) -
AMBRA1 is able to induce mitophagy via LC3 binding, regardless of PARKIN and p62/SQSTM1
por: Strappazzon, F, et al.
Publicado: (2015) -
Loss of Ambra1 promotes melanoma growth and invasion
por: Di Leo, Luca, et al.
Publicado: (2021)