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Bioinspired bi-phasic 3D nanoflowers of MgO/Mg(OH)(2) coated melamine sponge as a novel bactericidal agent

By roughly mimicking the surface architectural design of dragonfly wings, novel bi-phasic 3D nanoflowers of MgO/Mg(OH)(2) were successfully synthesized via the electrospinning technique. The 3D nanoflowers were coated over a commercial melamine sponge and extensively characterized by SEM, XRD, FTIR,...

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Autores principales: Agarwal, Ashutosh, Senevirathna, Hasanthi L., Koo, Seok Hwee, Wong, Crystal Shie Lyeen, Lim, Terence Sey Kiat, Ng, Foo Cheong, Anariba, Franklin, Wu, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10432489/
https://www.ncbi.nlm.nih.gov/pubmed/37587205
http://dx.doi.org/10.1038/s41598-023-40336-w
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author Agarwal, Ashutosh
Senevirathna, Hasanthi L.
Koo, Seok Hwee
Wong, Crystal Shie Lyeen
Lim, Terence Sey Kiat
Ng, Foo Cheong
Anariba, Franklin
Wu, Ping
author_facet Agarwal, Ashutosh
Senevirathna, Hasanthi L.
Koo, Seok Hwee
Wong, Crystal Shie Lyeen
Lim, Terence Sey Kiat
Ng, Foo Cheong
Anariba, Franklin
Wu, Ping
author_sort Agarwal, Ashutosh
collection PubMed
description By roughly mimicking the surface architectural design of dragonfly wings, novel bi-phasic 3D nanoflowers of MgO/Mg(OH)(2) were successfully synthesized via the electrospinning technique. The 3D nanoflowers were coated over a commercial melamine sponge and extensively characterized by SEM, XRD, FTIR, and EDS. The formation of distinct dense 3D nano petals was revealed by SEM images whereby the mean petal thickness and mean distance between the adjacent petals were found to be 36 nm and 121 nm, respectively. The bactericidal activities of synthesized 3D nano-flowers coated melamine sponges were assessed against five different bacteria (Staphylococcus aureus, Enterococcus faecalis, Escherichia coli, Klebsiella pneumoniae, and Pseudomonas aeruginosa). This study demonstrated significant bactericidal activity of MgO/Mg(OH)(2) 3D nanoflowers coated MS against Gram-positive and Gram-negative bacteria. Plausible bactericidal mechanisms include envelope deformation, penetration, and induction of oxidative stress. This study introduces novel bioinspired biomaterial with the capacity to reduce the risk associated with pathogenic bacterial infections, especially in medical devices.
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spelling pubmed-104324892023-08-18 Bioinspired bi-phasic 3D nanoflowers of MgO/Mg(OH)(2) coated melamine sponge as a novel bactericidal agent Agarwal, Ashutosh Senevirathna, Hasanthi L. Koo, Seok Hwee Wong, Crystal Shie Lyeen Lim, Terence Sey Kiat Ng, Foo Cheong Anariba, Franklin Wu, Ping Sci Rep Article By roughly mimicking the surface architectural design of dragonfly wings, novel bi-phasic 3D nanoflowers of MgO/Mg(OH)(2) were successfully synthesized via the electrospinning technique. The 3D nanoflowers were coated over a commercial melamine sponge and extensively characterized by SEM, XRD, FTIR, and EDS. The formation of distinct dense 3D nano petals was revealed by SEM images whereby the mean petal thickness and mean distance between the adjacent petals were found to be 36 nm and 121 nm, respectively. The bactericidal activities of synthesized 3D nano-flowers coated melamine sponges were assessed against five different bacteria (Staphylococcus aureus, Enterococcus faecalis, Escherichia coli, Klebsiella pneumoniae, and Pseudomonas aeruginosa). This study demonstrated significant bactericidal activity of MgO/Mg(OH)(2) 3D nanoflowers coated MS against Gram-positive and Gram-negative bacteria. Plausible bactericidal mechanisms include envelope deformation, penetration, and induction of oxidative stress. This study introduces novel bioinspired biomaterial with the capacity to reduce the risk associated with pathogenic bacterial infections, especially in medical devices. Nature Publishing Group UK 2023-08-16 /pmc/articles/PMC10432489/ /pubmed/37587205 http://dx.doi.org/10.1038/s41598-023-40336-w Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Agarwal, Ashutosh
Senevirathna, Hasanthi L.
Koo, Seok Hwee
Wong, Crystal Shie Lyeen
Lim, Terence Sey Kiat
Ng, Foo Cheong
Anariba, Franklin
Wu, Ping
Bioinspired bi-phasic 3D nanoflowers of MgO/Mg(OH)(2) coated melamine sponge as a novel bactericidal agent
title Bioinspired bi-phasic 3D nanoflowers of MgO/Mg(OH)(2) coated melamine sponge as a novel bactericidal agent
title_full Bioinspired bi-phasic 3D nanoflowers of MgO/Mg(OH)(2) coated melamine sponge as a novel bactericidal agent
title_fullStr Bioinspired bi-phasic 3D nanoflowers of MgO/Mg(OH)(2) coated melamine sponge as a novel bactericidal agent
title_full_unstemmed Bioinspired bi-phasic 3D nanoflowers of MgO/Mg(OH)(2) coated melamine sponge as a novel bactericidal agent
title_short Bioinspired bi-phasic 3D nanoflowers of MgO/Mg(OH)(2) coated melamine sponge as a novel bactericidal agent
title_sort bioinspired bi-phasic 3d nanoflowers of mgo/mg(oh)(2) coated melamine sponge as a novel bactericidal agent
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10432489/
https://www.ncbi.nlm.nih.gov/pubmed/37587205
http://dx.doi.org/10.1038/s41598-023-40336-w
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