Whole genome deconvolution unveils Alzheimer’s resilient epigenetic signature

Assay for Transposase Accessible Chromatin by sequencing (ATAC-seq) accurately depicts the chromatin regulatory state and altered mechanisms guiding gene expression in disease. However, bulk sequencing entangles information from different cell types and obscures cellular heterogeneity. To address th...

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Detalles Bibliográficos
Autores principales: Berson, Eloise, Sreenivas, Anjali, Phongpreecha, Thanaphong, Perna, Amalia, Grandi, Fiorella C., Xue, Lei, Ravindra, Neal G., Payrovnaziri, Neelufar, Mataraso, Samson, Kim, Yeasul, Espinosa, Camilo, Chang, Alan L., Becker, Martin, Montine, Kathleen S., Fox, Edward J., Chang, Howard Y., Corces, M. Ryan, Aghaeepour, Nima, Montine, Thomas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10432546/
https://www.ncbi.nlm.nih.gov/pubmed/37587197
http://dx.doi.org/10.1038/s41467-023-40611-4

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