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RTEL1 and MCM10 overcome topological stress during vertebrate replication termination
Topological stress can cause converging replication forks to stall during termination of vertebrate DNA synthesis. However, replication forks ultimately overcome fork stalling, suggesting that alternative mechanisms of termination exist. Using proteomics in Xenopus egg extracts, we show that the hel...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10432576/ https://www.ncbi.nlm.nih.gov/pubmed/36807139 http://dx.doi.org/10.1016/j.celrep.2023.112109 |