RTEL1 and MCM10 overcome topological stress during vertebrate replication termination

Topological stress can cause converging replication forks to stall during termination of vertebrate DNA synthesis. However, replication forks ultimately overcome fork stalling, suggesting that alternative mechanisms of termination exist. Using proteomics in Xenopus egg extracts, we show that the hel...

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Detalles Bibliográficos
Autores principales: Campos, Lillian V., Van Ravenstein, Sabrina X., Vontalge, Emma J., Greer, Briana H., Heintzman, Darren R., Kavlashvili, Tamar, McDonald, W. Hayes, Rose, Kristie Lindsey, Eichman, Brandt F., Dewar, James M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10432576/
https://www.ncbi.nlm.nih.gov/pubmed/36807139
http://dx.doi.org/10.1016/j.celrep.2023.112109

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