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Blood pressure pattern among blood donors exposed to SARS‐CoV‐2 in Luanda, Angola: A retrospective study
BACKGROUND AND AIMS: SARS‐CoV‐2 infection is a public health concern. Several aspects related to the pattern of infection remain unclear. This study aimed to investigate the blood pressure pattern among blood donors exposed to SARS‐CoV‐2 in Luanda, Angola, a sub‐Saharan African country. METHODS: We...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10432586/ https://www.ncbi.nlm.nih.gov/pubmed/37599663 http://dx.doi.org/10.1002/hsr2.1498 |
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author | Sebastião, Cruz S. Sacomboio, Euclides Francisco, Ngiambudulu M. Cassinela, Edson K. Mateus, António David, Zinga Pimentel, Victor Paixão, Joana Neto de Vasconcelos, Jocelyne Morais, Joana |
author_facet | Sebastião, Cruz S. Sacomboio, Euclides Francisco, Ngiambudulu M. Cassinela, Edson K. Mateus, António David, Zinga Pimentel, Victor Paixão, Joana Neto de Vasconcelos, Jocelyne Morais, Joana |
author_sort | Sebastião, Cruz S. |
collection | PubMed |
description | BACKGROUND AND AIMS: SARS‐CoV‐2 infection is a public health concern. Several aspects related to the pattern of infection remain unclear. This study aimed to investigate the blood pressure pattern among blood donors exposed to SARS‐CoV‐2 in Luanda, Angola, a sub‐Saharan African country. METHODS: We performed a retrospective analysis containing 343 blood donors from December 2019 to September 2020. Parametric tests compared means while χ (2) and logistic regression checked features associated with high blood pressure and were considered significant when p < 0.05. RESULTS: The mean age of blood donors was 32.2 ± 8.81 years (ranging from 18 to 61 years) and 93% of the men's gender. Overall, 4.7% of the studied population had been exposed to SARS‐CoV‐2. High blood pressure prevalence increased from unexposed to exposed SARS‐CoV‐2 (6.7%–18.8%, p = 0.071). SARS‐CoV‐2 exposure increase systole (131 ± 12.2 mmHg to 136 ± 14.2 mmHg, p = 0.098), diastole (79.9 ± 9.53 mmHg to 84.2 ± 12.7 mmHg, p = 0.086), pulse in beats per minute (72.0 ± 11.1 to 73.7 ± 8.50, p = 0.553), and decrease donating time (6.31 ± 3.72 min to 5.48 ± 1.61 min, p = 0.371). Chances of having high blood pressure were high [OR: 3.20 (95% confidence interval [CI]: 0.85–12.1), p = 0.086] in exposed SARS‐CoV‐2. Donors exposed to SARS‐CoV‐2 with abnormal donation time increased from the donor up to 40 years to over 40 years (from 35.7% to 50%, p = 0.696). The mean systolic, diastolic, and pulse pressure were higher for non‐O donors (p > 0.05). A significant link was observed, between the Rhesus factor and blood pressure status (p = 0.032). CONCLUSION: We showed important variations in blood pressure indices of the Angolan population exposed to SARS‐CoV‐2. Older age and non‐O blood groups appear to be important biological factors for SARS‐CoV‐2 infection, as well as the risk of developing cardiovascular disease after or during SARS‐CoV‐2 exposure. Further studies assessing the impact on cardiovascular functions with ongoing or long‐term SARS‐CoV‐2 exposure in individuals from resource‐limited countries should be considered. |
format | Online Article Text |
id | pubmed-10432586 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-104325862023-08-18 Blood pressure pattern among blood donors exposed to SARS‐CoV‐2 in Luanda, Angola: A retrospective study Sebastião, Cruz S. Sacomboio, Euclides Francisco, Ngiambudulu M. Cassinela, Edson K. Mateus, António David, Zinga Pimentel, Victor Paixão, Joana Neto de Vasconcelos, Jocelyne Morais, Joana Health Sci Rep Original Research BACKGROUND AND AIMS: SARS‐CoV‐2 infection is a public health concern. Several aspects related to the pattern of infection remain unclear. This study aimed to investigate the blood pressure pattern among blood donors exposed to SARS‐CoV‐2 in Luanda, Angola, a sub‐Saharan African country. METHODS: We performed a retrospective analysis containing 343 blood donors from December 2019 to September 2020. Parametric tests compared means while χ (2) and logistic regression checked features associated with high blood pressure and were considered significant when p < 0.05. RESULTS: The mean age of blood donors was 32.2 ± 8.81 years (ranging from 18 to 61 years) and 93% of the men's gender. Overall, 4.7% of the studied population had been exposed to SARS‐CoV‐2. High blood pressure prevalence increased from unexposed to exposed SARS‐CoV‐2 (6.7%–18.8%, p = 0.071). SARS‐CoV‐2 exposure increase systole (131 ± 12.2 mmHg to 136 ± 14.2 mmHg, p = 0.098), diastole (79.9 ± 9.53 mmHg to 84.2 ± 12.7 mmHg, p = 0.086), pulse in beats per minute (72.0 ± 11.1 to 73.7 ± 8.50, p = 0.553), and decrease donating time (6.31 ± 3.72 min to 5.48 ± 1.61 min, p = 0.371). Chances of having high blood pressure were high [OR: 3.20 (95% confidence interval [CI]: 0.85–12.1), p = 0.086] in exposed SARS‐CoV‐2. Donors exposed to SARS‐CoV‐2 with abnormal donation time increased from the donor up to 40 years to over 40 years (from 35.7% to 50%, p = 0.696). The mean systolic, diastolic, and pulse pressure were higher for non‐O donors (p > 0.05). A significant link was observed, between the Rhesus factor and blood pressure status (p = 0.032). CONCLUSION: We showed important variations in blood pressure indices of the Angolan population exposed to SARS‐CoV‐2. Older age and non‐O blood groups appear to be important biological factors for SARS‐CoV‐2 infection, as well as the risk of developing cardiovascular disease after or during SARS‐CoV‐2 exposure. Further studies assessing the impact on cardiovascular functions with ongoing or long‐term SARS‐CoV‐2 exposure in individuals from resource‐limited countries should be considered. John Wiley and Sons Inc. 2023-08-16 /pmc/articles/PMC10432586/ /pubmed/37599663 http://dx.doi.org/10.1002/hsr2.1498 Text en © 2023 The Authors. Health Science Reports published by Wiley Periodicals LLC. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Research Sebastião, Cruz S. Sacomboio, Euclides Francisco, Ngiambudulu M. Cassinela, Edson K. Mateus, António David, Zinga Pimentel, Victor Paixão, Joana Neto de Vasconcelos, Jocelyne Morais, Joana Blood pressure pattern among blood donors exposed to SARS‐CoV‐2 in Luanda, Angola: A retrospective study |
title | Blood pressure pattern among blood donors exposed to SARS‐CoV‐2 in Luanda, Angola: A retrospective study |
title_full | Blood pressure pattern among blood donors exposed to SARS‐CoV‐2 in Luanda, Angola: A retrospective study |
title_fullStr | Blood pressure pattern among blood donors exposed to SARS‐CoV‐2 in Luanda, Angola: A retrospective study |
title_full_unstemmed | Blood pressure pattern among blood donors exposed to SARS‐CoV‐2 in Luanda, Angola: A retrospective study |
title_short | Blood pressure pattern among blood donors exposed to SARS‐CoV‐2 in Luanda, Angola: A retrospective study |
title_sort | blood pressure pattern among blood donors exposed to sars‐cov‐2 in luanda, angola: a retrospective study |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10432586/ https://www.ncbi.nlm.nih.gov/pubmed/37599663 http://dx.doi.org/10.1002/hsr2.1498 |
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