Trastuzumab-induced human cardiomyocyte damage through the Notch2/JAK2/STAT3 pathway

OBJECTIVE: Trastuzumab is the preferred drug for the treatment of breast cancer. However, research on the cellular mechanisms of trastuzumab's potential cardiotoxicity is insufficient. The purpose of this study was to explore the toxic effects and potential mechanism of action of trastuzumab on...

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Detalles Bibliográficos
Autores principales: Su, Zhenbo, Liu, Siyao, Zou, Yinggang, Shan, Liang, Yu, Miao, Xie, Shishun, Li, Xiangjun, Jin, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo 2023
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10432602/
https://www.ncbi.nlm.nih.gov/pubmed/37567042
http://dx.doi.org/10.1016/j.clinsp.2023.100268

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