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Impact of a teen club model on HIV outcomes among adolescents in rural Neno district, Malawi: a retrospective cohort study

OBJECTIVE: To compare the impact of a teen club model to the standard care model on HIV treatment outcomes among adolescents (10–19 years of age). DESIGN: Retrospective cohort study. SETTING: HIV clinics in Neno district, Malawi. PARTICIPANTS: Adolescents living with HIV enrolled in teen clubs (n=23...

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Autores principales: Trapence, Clement Patrick, Kanyenda, Chisomo, Muyila, Fainala, Ndarama, Enoch PL, Suffrin, Dimitri, Connolly, Emilia, Kachimanga, Chiyembekezo, Kulinkina, Alexandra V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10432624/
https://www.ncbi.nlm.nih.gov/pubmed/37586863
http://dx.doi.org/10.1136/bmjopen-2022-069870
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author Trapence, Clement Patrick
Kanyenda, Chisomo
Muyila, Fainala
Ndarama, Enoch PL
Suffrin, Dimitri
Connolly, Emilia
Kachimanga, Chiyembekezo
Kulinkina, Alexandra V
author_facet Trapence, Clement Patrick
Kanyenda, Chisomo
Muyila, Fainala
Ndarama, Enoch PL
Suffrin, Dimitri
Connolly, Emilia
Kachimanga, Chiyembekezo
Kulinkina, Alexandra V
author_sort Trapence, Clement Patrick
collection PubMed
description OBJECTIVE: To compare the impact of a teen club model to the standard care model on HIV treatment outcomes among adolescents (10–19 years of age). DESIGN: Retrospective cohort study. SETTING: HIV clinics in Neno district, Malawi. PARTICIPANTS: Adolescents living with HIV enrolled in teen clubs (n=235) and matched participants in standard HIV care (n=297). OUTCOME MEASURES: Attrition from HIV care, defined as a combination of treatment outcomes ‘died’, ‘defaulted’ and ‘transferred out’. RESULTS: Over a 4-year follow-up period, adolescents who participated in the teen club had a significantly higher likelihood of remaining in care than those who did not (HR=2.80; 95% CI: 1.46 to 5.34). Teen clubs also increased the probability of having a recent measured viral load (VL) and BMI, but did not change the probability of VL suppression. The age at antiretroviral treatment initiation below 15 years (aHR=0.37; 95% CI: 0.17 to 0.82) reduced the risk of attrition from HIV care, while underweight status (aHR=3.18; 95% CI: 1.71 to 5.92) increased the risk of attrition, after controlling for sex, WHO HIV staging and teen club participation. CONCLUSIONS: The teen club model has the potential to improve treatment outcomes among adolescents in rural Neno district. However, in addition to retaining adolescents in HIV care, greater attention is needed to treatment adherence and viral suppression in this special population. Further understanding of the contextual factors and barriers that adolescents in rural areas face could further improve the teen club model to ensure high-quality HIV care and quality of life.
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spelling pubmed-104326242023-08-18 Impact of a teen club model on HIV outcomes among adolescents in rural Neno district, Malawi: a retrospective cohort study Trapence, Clement Patrick Kanyenda, Chisomo Muyila, Fainala Ndarama, Enoch PL Suffrin, Dimitri Connolly, Emilia Kachimanga, Chiyembekezo Kulinkina, Alexandra V BMJ Open HIV/AIDS OBJECTIVE: To compare the impact of a teen club model to the standard care model on HIV treatment outcomes among adolescents (10–19 years of age). DESIGN: Retrospective cohort study. SETTING: HIV clinics in Neno district, Malawi. PARTICIPANTS: Adolescents living with HIV enrolled in teen clubs (n=235) and matched participants in standard HIV care (n=297). OUTCOME MEASURES: Attrition from HIV care, defined as a combination of treatment outcomes ‘died’, ‘defaulted’ and ‘transferred out’. RESULTS: Over a 4-year follow-up period, adolescents who participated in the teen club had a significantly higher likelihood of remaining in care than those who did not (HR=2.80; 95% CI: 1.46 to 5.34). Teen clubs also increased the probability of having a recent measured viral load (VL) and BMI, but did not change the probability of VL suppression. The age at antiretroviral treatment initiation below 15 years (aHR=0.37; 95% CI: 0.17 to 0.82) reduced the risk of attrition from HIV care, while underweight status (aHR=3.18; 95% CI: 1.71 to 5.92) increased the risk of attrition, after controlling for sex, WHO HIV staging and teen club participation. CONCLUSIONS: The teen club model has the potential to improve treatment outcomes among adolescents in rural Neno district. However, in addition to retaining adolescents in HIV care, greater attention is needed to treatment adherence and viral suppression in this special population. Further understanding of the contextual factors and barriers that adolescents in rural areas face could further improve the teen club model to ensure high-quality HIV care and quality of life. BMJ Publishing Group 2023-08-16 /pmc/articles/PMC10432624/ /pubmed/37586863 http://dx.doi.org/10.1136/bmjopen-2022-069870 Text en © Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) .
spellingShingle HIV/AIDS
Trapence, Clement Patrick
Kanyenda, Chisomo
Muyila, Fainala
Ndarama, Enoch PL
Suffrin, Dimitri
Connolly, Emilia
Kachimanga, Chiyembekezo
Kulinkina, Alexandra V
Impact of a teen club model on HIV outcomes among adolescents in rural Neno district, Malawi: a retrospective cohort study
title Impact of a teen club model on HIV outcomes among adolescents in rural Neno district, Malawi: a retrospective cohort study
title_full Impact of a teen club model on HIV outcomes among adolescents in rural Neno district, Malawi: a retrospective cohort study
title_fullStr Impact of a teen club model on HIV outcomes among adolescents in rural Neno district, Malawi: a retrospective cohort study
title_full_unstemmed Impact of a teen club model on HIV outcomes among adolescents in rural Neno district, Malawi: a retrospective cohort study
title_short Impact of a teen club model on HIV outcomes among adolescents in rural Neno district, Malawi: a retrospective cohort study
title_sort impact of a teen club model on hiv outcomes among adolescents in rural neno district, malawi: a retrospective cohort study
topic HIV/AIDS
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10432624/
https://www.ncbi.nlm.nih.gov/pubmed/37586863
http://dx.doi.org/10.1136/bmjopen-2022-069870
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