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Immune dysfunction revealed by digital spatial profiling of immuno-oncology markers in progressive stages of renal cell carcinoma and in brain metastases

BACKGROUND: The tumor microenvironment (TME) contributes to cancer progression and treatment response to therapy, including in renal cell carcinoma (RCC). Prior profiling studies, including single-cell transcriptomics, often involve limited sample sizes and lack spatial orientation. The TME of RCC b...

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Detalles Bibliográficos
Autores principales:	Schoenfeld, David A, Moutafi, Myrto, Martinez, Sandra, Djureinovic, Dijana, Merkin, Ross D, Adeniran, Adebowale, Braun, David A, Signoretti, Sabina, Choueiri, Toni K, Parisi, Fabio, Hurwitz, Michael, Rimm, David L, Wei, Wei, Jilaveanu, Lucia, Kluger, Harriet M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2023
Materias:	Immunotherapy Biomarkers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10432651/ https://www.ncbi.nlm.nih.gov/pubmed/37586773 http://dx.doi.org/10.1136/jitc-2023-007240

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