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A Msp1-containing complex removes orphaned proteins in the mitochondrial outer membrane of T. brucei

The AAA-ATPase Msp1 extracts mislocalised outer membrane proteins and thus contributes to mitochondrial proteostasis. Using pulldown experiments, we show that trypanosomal Msp1 localises to both glycosomes and the mitochondrial outer membrane, where it forms a complex with four outer membrane protei...

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Detalles Bibliográficos
Autores principales: Gerber, Markus, Suppanz, Ida, Oeljeklaus, Silke, Niemann, Moritz, Käser, Sandro, Warscheid, Bettina, Schneider, André, Dewar, Caroline E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10432679/
https://www.ncbi.nlm.nih.gov/pubmed/37586887
http://dx.doi.org/10.26508/lsa.202302004