Vascular endothelial profilin-1 drives a protumorigenic tumor microenvironment and tumor progression in renal cancer

Overexpression of actin-binding protein profilin-1 (Pfn1) correlates with advanced disease features and adverse clinical outcome of patients with clear cell renal carcinoma, the most prevalent form of renal cancer. We previously reported that Pfn1 is predominantly overexpressed in tumor-associated v...

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Detalles Bibliográficos
Autores principales: Gau, David, Daoud, Andrew, Allen, Abigail, Joy, Marion, Sagan, April, Lee, Sanghoon, Lucas, Peter C., Duensing, Stefan, Boone, David, Osmanbeyoglu, Hatice U., Roy, Partha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10432806/
https://www.ncbi.nlm.nih.gov/pubmed/37451478
http://dx.doi.org/10.1016/j.jbc.2023.105044

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