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Mammalian type opsin 5 preferentially activates G14 in Gq-type G proteins triggering intracellular calcium response

Mammalian type opsin 5 (Opn5m), a UV-sensitive G protein–coupled receptor opsin highly conserved in vertebrates, would provide a common basis for UV sensing from lamprey to humans. However, G protein coupled with Opn5m remains controversial due to variations in assay conditions and the origin of Opn...

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Detalles Bibliográficos
Autores principales: Sato, Keita, Yamashita, Takahiro, Ohuchi, Hideyo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10432815/
https://www.ncbi.nlm.nih.gov/pubmed/37423300
http://dx.doi.org/10.1016/j.jbc.2023.105020

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