EV-mediated promotion of myogenic differentiation is dependent on dose, collection medium, and isolation method

Extracellular vesicles (EVs) have been implicated in the regulation of myogenic differentiation. C2C12 murine myoblast differentiation was reduced following treatment with GW4869 or heparin (to inhibit exosome biogenesis and EV uptake, respectively). Conversely, treatment with C2C12 myotube-conditio...

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Detalles Bibliográficos
Autores principales: Hanson, Britt, Vorobieva, Ioulia, Zheng, Wenyi, Conceição, Mariana, Lomonosova, Yulia, Mäger, Imre, Puri, Pier Lorenzo, El Andaloussi, Samir, Wood, Matthew J.A., Roberts, Thomas C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10432918/
https://www.ncbi.nlm.nih.gov/pubmed/37602275
http://dx.doi.org/10.1016/j.omtn.2023.07.005

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