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Multiple routes of communication within the amygdala-mPFC network: A comparative approach in humans and macaques
The network formed by the amygdala (AMG) and the medial Prefrontal Cortex (mPFC), at the interface between our internal and external environment, has been shown to support some important aspects of behavioral adaptation. Whether and how the anatomo-functional organization of this network evolved acr...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10432920/ https://www.ncbi.nlm.nih.gov/pubmed/37601951 http://dx.doi.org/10.1016/j.crneur.2023.100103 |
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author | Giacometti, C. Amiez, C. Hadj-Bouziane, F. |
author_facet | Giacometti, C. Amiez, C. Hadj-Bouziane, F. |
author_sort | Giacometti, C. |
collection | PubMed |
description | The network formed by the amygdala (AMG) and the medial Prefrontal Cortex (mPFC), at the interface between our internal and external environment, has been shown to support some important aspects of behavioral adaptation. Whether and how the anatomo-functional organization of this network evolved across primates remains unclear. Here, we compared AMG nuclei morphological characteristics and their functional connectivity with the mPFC in humans and macaques to identify potential homologies and differences between these species. Based on selected studies, we highlight two subsystems within the AMG-mPFC circuits, likely involved in distinct temporal dynamics of integration during behavioral adaptation. We also show that whereas the mPFC displays a large expansion but a preserved intrinsic anatomo-functional organization, the AMG displays a volume reduction and morphological changes related to specific nuclei. We discuss potential commonalities and differences in the dialogue between AMG nuclei and mPFC in humans and macaques based on available data. |
format | Online Article Text |
id | pubmed-10432920 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-104329202023-08-18 Multiple routes of communication within the amygdala-mPFC network: A comparative approach in humans and macaques Giacometti, C. Amiez, C. Hadj-Bouziane, F. Curr Res Neurobiol Review Article The network formed by the amygdala (AMG) and the medial Prefrontal Cortex (mPFC), at the interface between our internal and external environment, has been shown to support some important aspects of behavioral adaptation. Whether and how the anatomo-functional organization of this network evolved across primates remains unclear. Here, we compared AMG nuclei morphological characteristics and their functional connectivity with the mPFC in humans and macaques to identify potential homologies and differences between these species. Based on selected studies, we highlight two subsystems within the AMG-mPFC circuits, likely involved in distinct temporal dynamics of integration during behavioral adaptation. We also show that whereas the mPFC displays a large expansion but a preserved intrinsic anatomo-functional organization, the AMG displays a volume reduction and morphological changes related to specific nuclei. We discuss potential commonalities and differences in the dialogue between AMG nuclei and mPFC in humans and macaques based on available data. Elsevier 2023-07-28 /pmc/articles/PMC10432920/ /pubmed/37601951 http://dx.doi.org/10.1016/j.crneur.2023.100103 Text en © 2023 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Review Article Giacometti, C. Amiez, C. Hadj-Bouziane, F. Multiple routes of communication within the amygdala-mPFC network: A comparative approach in humans and macaques |
title | Multiple routes of communication within the amygdala-mPFC network: A comparative approach in humans and macaques |
title_full | Multiple routes of communication within the amygdala-mPFC network: A comparative approach in humans and macaques |
title_fullStr | Multiple routes of communication within the amygdala-mPFC network: A comparative approach in humans and macaques |
title_full_unstemmed | Multiple routes of communication within the amygdala-mPFC network: A comparative approach in humans and macaques |
title_short | Multiple routes of communication within the amygdala-mPFC network: A comparative approach in humans and macaques |
title_sort | multiple routes of communication within the amygdala-mpfc network: a comparative approach in humans and macaques |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10432920/ https://www.ncbi.nlm.nih.gov/pubmed/37601951 http://dx.doi.org/10.1016/j.crneur.2023.100103 |
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