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Area deprivation and demographic factors associated with diabetes technology use in adults with type 1 diabetes in Germany

INTRODUCTION: Diabetes technology improves glycemic control and quality of life for many people with type 1 diabetes (T1D). However, inequalities in access to diabetes technology exist in many countries. In Germany, disparities in technology use have been described in pediatric T1D, but no data for...

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Autores principales: Auzanneau, Marie, Eckert, Alexander J., Meyhöfer, Sebastian M., Heni, Martin, Gillessen, Anton, Schwettmann, Lars, Jehle, Peter M., Hummel, Michael, Holl, Reinhard W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10433185/
https://www.ncbi.nlm.nih.gov/pubmed/37600703
http://dx.doi.org/10.3389/fendo.2023.1191138
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author Auzanneau, Marie
Eckert, Alexander J.
Meyhöfer, Sebastian M.
Heni, Martin
Gillessen, Anton
Schwettmann, Lars
Jehle, Peter M.
Hummel, Michael
Holl, Reinhard W.
author_facet Auzanneau, Marie
Eckert, Alexander J.
Meyhöfer, Sebastian M.
Heni, Martin
Gillessen, Anton
Schwettmann, Lars
Jehle, Peter M.
Hummel, Michael
Holl, Reinhard W.
author_sort Auzanneau, Marie
collection PubMed
description INTRODUCTION: Diabetes technology improves glycemic control and quality of life for many people with type 1 diabetes (T1D). However, inequalities in access to diabetes technology exist in many countries. In Germany, disparities in technology use have been described in pediatric T1D, but no data for adults are available so far. We therefore aimed to analyze whether demographic factors and area deprivation are associated with technology use in a representative population of adults with T1D. MATERIALS AND METHODS: In adults with T1D from the German prospective diabetes follow-up registry (DPV), we analyzed the use of continuous subcutaneous insulin infusion (CSII), continuous glucose monitoring (CGM), and sensor augmented pump therapy (SAP, with and without automated insulin delivery) in 2019-2021 by age group, gender, migration background, and area deprivation using multiple adjusted regression models. Area deprivation, defined as a relative lack of area-based resources, was measured by quintiles of the German index of Multiple Deprivation (GIMD 2015, from Q1, least deprived, to Q5, most deprived districts). RESULTS: Among 13,351 adults with T1D, the use of technology decreased significantly with older age: CSII use fell from 56.1% in the 18−<25-year age group to 3.1% in the ≥80-year age group, CGM use from 75.3% to 28.2%, and SAP use from 45.1% to 1.5% (all p for trend <0.001). The use of technology was also significantly higher in women than in men (CSII: 39.2% vs. 27.6%; CGM: 61.9% vs. 58.0%; SAP: 28.7% vs. 19.6%, all p <0.001), and in individuals without migration background than in those with migration background (CSII: 38.8% vs. 27.6%; CGM: 71.1% vs. 61.4%; SAP: 30.5% vs. 21.3%, all p <0.001). Associations with area deprivation were not linear: the use of each technology decreased only from Q2 to Q4. DISCUSSION: Our real-world data provide evidence that higher age, male gender, and migration background are currently associated with lower use of diabetes technology in adults with T1D in Germany. Associations with area deprivation are more complex, probably due to correlations with other factors, like the higher proportion of migrants in less deprived areas or the federal structure of the German health care system.
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spelling pubmed-104331852023-08-18 Area deprivation and demographic factors associated with diabetes technology use in adults with type 1 diabetes in Germany Auzanneau, Marie Eckert, Alexander J. Meyhöfer, Sebastian M. Heni, Martin Gillessen, Anton Schwettmann, Lars Jehle, Peter M. Hummel, Michael Holl, Reinhard W. Front Endocrinol (Lausanne) Endocrinology INTRODUCTION: Diabetes technology improves glycemic control and quality of life for many people with type 1 diabetes (T1D). However, inequalities in access to diabetes technology exist in many countries. In Germany, disparities in technology use have been described in pediatric T1D, but no data for adults are available so far. We therefore aimed to analyze whether demographic factors and area deprivation are associated with technology use in a representative population of adults with T1D. MATERIALS AND METHODS: In adults with T1D from the German prospective diabetes follow-up registry (DPV), we analyzed the use of continuous subcutaneous insulin infusion (CSII), continuous glucose monitoring (CGM), and sensor augmented pump therapy (SAP, with and without automated insulin delivery) in 2019-2021 by age group, gender, migration background, and area deprivation using multiple adjusted regression models. Area deprivation, defined as a relative lack of area-based resources, was measured by quintiles of the German index of Multiple Deprivation (GIMD 2015, from Q1, least deprived, to Q5, most deprived districts). RESULTS: Among 13,351 adults with T1D, the use of technology decreased significantly with older age: CSII use fell from 56.1% in the 18−<25-year age group to 3.1% in the ≥80-year age group, CGM use from 75.3% to 28.2%, and SAP use from 45.1% to 1.5% (all p for trend <0.001). The use of technology was also significantly higher in women than in men (CSII: 39.2% vs. 27.6%; CGM: 61.9% vs. 58.0%; SAP: 28.7% vs. 19.6%, all p <0.001), and in individuals without migration background than in those with migration background (CSII: 38.8% vs. 27.6%; CGM: 71.1% vs. 61.4%; SAP: 30.5% vs. 21.3%, all p <0.001). Associations with area deprivation were not linear: the use of each technology decreased only from Q2 to Q4. DISCUSSION: Our real-world data provide evidence that higher age, male gender, and migration background are currently associated with lower use of diabetes technology in adults with T1D in Germany. Associations with area deprivation are more complex, probably due to correlations with other factors, like the higher proportion of migrants in less deprived areas or the federal structure of the German health care system. Frontiers Media S.A. 2023-08-01 /pmc/articles/PMC10433185/ /pubmed/37600703 http://dx.doi.org/10.3389/fendo.2023.1191138 Text en Copyright © 2023 Auzanneau, Eckert, Meyhöfer, Heni, Gillessen, Schwettmann, Jehle, Hummel and Holl https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Endocrinology
Auzanneau, Marie
Eckert, Alexander J.
Meyhöfer, Sebastian M.
Heni, Martin
Gillessen, Anton
Schwettmann, Lars
Jehle, Peter M.
Hummel, Michael
Holl, Reinhard W.
Area deprivation and demographic factors associated with diabetes technology use in adults with type 1 diabetes in Germany
title Area deprivation and demographic factors associated with diabetes technology use in adults with type 1 diabetes in Germany
title_full Area deprivation and demographic factors associated with diabetes technology use in adults with type 1 diabetes in Germany
title_fullStr Area deprivation and demographic factors associated with diabetes technology use in adults with type 1 diabetes in Germany
title_full_unstemmed Area deprivation and demographic factors associated with diabetes technology use in adults with type 1 diabetes in Germany
title_short Area deprivation and demographic factors associated with diabetes technology use in adults with type 1 diabetes in Germany
title_sort area deprivation and demographic factors associated with diabetes technology use in adults with type 1 diabetes in germany
topic Endocrinology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10433185/
https://www.ncbi.nlm.nih.gov/pubmed/37600703
http://dx.doi.org/10.3389/fendo.2023.1191138
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