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Effect of add-on devices with projections on screening colonoscopy: a systematic review and meta-analysis

BACKGROUND: Add-on devices with projections, e.g., Endocuff, Endocuff Vision, EndoRings, and Wingcap, placed on the distal tip of the colonoscope promise to improve the detection of precancerous lesions. We performed a meta-analysis to evaluate the performance of these devices exclusively among indi...

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Autores principales: Manti, Magdalini, Tziatzios, Georgios, Facciorusso, Antonio, Papaefthymiou, Apostolis, Ramai, Daryl, Papanikolaou, Ioannis, Hassan, Cesare, Triantafyllou, Konstantinos, Paraskeva, Konstantina, Gkolfakis, Paraskevas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hellenic Society of Gastroenterology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10433254/
https://www.ncbi.nlm.nih.gov/pubmed/37664236
http://dx.doi.org/10.20524/aog.2023.0820
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author Manti, Magdalini
Tziatzios, Georgios
Facciorusso, Antonio
Papaefthymiou, Apostolis
Ramai, Daryl
Papanikolaou, Ioannis
Hassan, Cesare
Triantafyllou, Konstantinos
Paraskeva, Konstantina
Gkolfakis, Paraskevas
author_facet Manti, Magdalini
Tziatzios, Georgios
Facciorusso, Antonio
Papaefthymiou, Apostolis
Ramai, Daryl
Papanikolaou, Ioannis
Hassan, Cesare
Triantafyllou, Konstantinos
Paraskeva, Konstantina
Gkolfakis, Paraskevas
author_sort Manti, Magdalini
collection PubMed
description BACKGROUND: Add-on devices with projections, e.g., Endocuff, Endocuff Vision, EndoRings, and Wingcap, placed on the distal tip of the colonoscope promise to improve the detection of precancerous lesions. We performed a meta-analysis to evaluate the performance of these devices exclusively among individuals undergoing colonoscopy for screening purpose. METHODS: A computerized literature search was performed across MEDLINE and Cochrane Library databases for randomized controlled trials that compared standard colonoscopy (SC) to procedures using add-on devices. The primary outcome was adenoma detection rate (ADR), while secondary outcomes included polyp detection rate (PDR), advanced ADR (AADR), and sessile serrated lesion detection rate (SSLDR). The effect size on study outcomes was calculated using a random-effects model and presented as the risk ratio (RR) and 95% confidence interval (CI). RESULTS: Seven studies enrolling a total of 5785 patients were included. The use of add-on-devices with projections was associated with a higher ADR compared to SC: 45.9% vs. 41.1%; RR 1.18, 95%CI 1.02-1.37; P=0.03; I(2)=79%. Although PDR was higher in screening colonoscopies assisted by add-on devices as compared to SC, the difference failed to reach significance: 55.1% vs. 50.8%; RR 1.10, 95%CI 0.96-1.26; P=0.17; I(2)=75%. No difference was found between procedures assisted by add-on devices with projections and SC colonoscopies in terms of AADR (18.5% vs. 17.6%; RR 1.00, 95%CI 0.79-1.27; P=0.98; I(2)=56%) or SSLDR (6.8% vs. 5.8%; RR 1.17, 95%CI 0.95-1.44; P=0.15; I(2)=0%). CONCLUSION: Colonoscopy assisted by add-on devices with projections achieves a better ADR compared to SC among individuals undergoing screening for bowel cancer.
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spelling pubmed-104332542023-09-01 Effect of add-on devices with projections on screening colonoscopy: a systematic review and meta-analysis Manti, Magdalini Tziatzios, Georgios Facciorusso, Antonio Papaefthymiou, Apostolis Ramai, Daryl Papanikolaou, Ioannis Hassan, Cesare Triantafyllou, Konstantinos Paraskeva, Konstantina Gkolfakis, Paraskevas Ann Gastroenterol Original Article BACKGROUND: Add-on devices with projections, e.g., Endocuff, Endocuff Vision, EndoRings, and Wingcap, placed on the distal tip of the colonoscope promise to improve the detection of precancerous lesions. We performed a meta-analysis to evaluate the performance of these devices exclusively among individuals undergoing colonoscopy for screening purpose. METHODS: A computerized literature search was performed across MEDLINE and Cochrane Library databases for randomized controlled trials that compared standard colonoscopy (SC) to procedures using add-on devices. The primary outcome was adenoma detection rate (ADR), while secondary outcomes included polyp detection rate (PDR), advanced ADR (AADR), and sessile serrated lesion detection rate (SSLDR). The effect size on study outcomes was calculated using a random-effects model and presented as the risk ratio (RR) and 95% confidence interval (CI). RESULTS: Seven studies enrolling a total of 5785 patients were included. The use of add-on-devices with projections was associated with a higher ADR compared to SC: 45.9% vs. 41.1%; RR 1.18, 95%CI 1.02-1.37; P=0.03; I(2)=79%. Although PDR was higher in screening colonoscopies assisted by add-on devices as compared to SC, the difference failed to reach significance: 55.1% vs. 50.8%; RR 1.10, 95%CI 0.96-1.26; P=0.17; I(2)=75%. No difference was found between procedures assisted by add-on devices with projections and SC colonoscopies in terms of AADR (18.5% vs. 17.6%; RR 1.00, 95%CI 0.79-1.27; P=0.98; I(2)=56%) or SSLDR (6.8% vs. 5.8%; RR 1.17, 95%CI 0.95-1.44; P=0.15; I(2)=0%). CONCLUSION: Colonoscopy assisted by add-on devices with projections achieves a better ADR compared to SC among individuals undergoing screening for bowel cancer. Hellenic Society of Gastroenterology 2023 2023-07-03 /pmc/articles/PMC10433254/ /pubmed/37664236 http://dx.doi.org/10.20524/aog.2023.0820 Text en Copyright: © Hellenic Society of Gastroenterology https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Manti, Magdalini
Tziatzios, Georgios
Facciorusso, Antonio
Papaefthymiou, Apostolis
Ramai, Daryl
Papanikolaou, Ioannis
Hassan, Cesare
Triantafyllou, Konstantinos
Paraskeva, Konstantina
Gkolfakis, Paraskevas
Effect of add-on devices with projections on screening colonoscopy: a systematic review and meta-analysis
title Effect of add-on devices with projections on screening colonoscopy: a systematic review and meta-analysis
title_full Effect of add-on devices with projections on screening colonoscopy: a systematic review and meta-analysis
title_fullStr Effect of add-on devices with projections on screening colonoscopy: a systematic review and meta-analysis
title_full_unstemmed Effect of add-on devices with projections on screening colonoscopy: a systematic review and meta-analysis
title_short Effect of add-on devices with projections on screening colonoscopy: a systematic review and meta-analysis
title_sort effect of add-on devices with projections on screening colonoscopy: a systematic review and meta-analysis
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10433254/
https://www.ncbi.nlm.nih.gov/pubmed/37664236
http://dx.doi.org/10.20524/aog.2023.0820
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