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Potential role of the gut microbiota of bumblebee Bombus pyrosoma in adaptation to high-altitude habitats

The gut microbiota affects the health and overall fitness of bumblebees. It can enhance the host's ecological range by leveraging their metabolic capacities. However, the diversity of the gut microbiota and adaptive functional evolution in high-altitude regions remain unclear. To explore how th...

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Autores principales: Zhang, Zhengyi, Guo, Yulong, Zhuang, Mingsheng, Liu, Fugang, Xia, Zhongyan, Zhang, Zhihao, Yang, Fan, Zeng, Huayan, Wu, Yueguo, Huang, Jiaxing, Li, Jilian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10433375/
https://www.ncbi.nlm.nih.gov/pubmed/37601385
http://dx.doi.org/10.3389/fmicb.2023.1218560
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author Zhang, Zhengyi
Guo, Yulong
Zhuang, Mingsheng
Liu, Fugang
Xia, Zhongyan
Zhang, Zhihao
Yang, Fan
Zeng, Huayan
Wu, Yueguo
Huang, Jiaxing
Li, Jilian
author_facet Zhang, Zhengyi
Guo, Yulong
Zhuang, Mingsheng
Liu, Fugang
Xia, Zhongyan
Zhang, Zhihao
Yang, Fan
Zeng, Huayan
Wu, Yueguo
Huang, Jiaxing
Li, Jilian
author_sort Zhang, Zhengyi
collection PubMed
description The gut microbiota affects the health and overall fitness of bumblebees. It can enhance the host's ecological range by leveraging their metabolic capacities. However, the diversity of the gut microbiota and adaptive functional evolution in high-altitude regions remain unclear. To explore how the gut microbiota helps the host adapt to high-altitude environments, we analyzed the differences in diversity and function of the gut microbiota between high- and low-altitude regions through full-length 16S rRNA sequencing. Our results show that high-altitude regions have a lower abundance of Fructobacillus and Saccharibacter compared to low-altitude regions. Additionally, some individuals in low-altitude regions were invaded by opportunistic pathogens. The gut microbiota in high-altitude regions has a greater number of pathways involved in “Protein digestion and absorption” and “Biosynthesis of amino acids,” while fewer carbohydrate pathways are involved in “digestion and absorption” and “Salmonella infection.” Our finding suggests that plateau hosts typically reduce energy metabolism and enhance immunity in response to adverse environments. Correspondingly, the gut microbiota also makes changes, such as reducing carbohydrate degradation and increasing protein utilization in response to the host. Additionally, the gut microbiota regulates their abundance and function to help the host adapt to adverse high-altitude environments.
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spelling pubmed-104333752023-08-18 Potential role of the gut microbiota of bumblebee Bombus pyrosoma in adaptation to high-altitude habitats Zhang, Zhengyi Guo, Yulong Zhuang, Mingsheng Liu, Fugang Xia, Zhongyan Zhang, Zhihao Yang, Fan Zeng, Huayan Wu, Yueguo Huang, Jiaxing Li, Jilian Front Microbiol Microbiology The gut microbiota affects the health and overall fitness of bumblebees. It can enhance the host's ecological range by leveraging their metabolic capacities. However, the diversity of the gut microbiota and adaptive functional evolution in high-altitude regions remain unclear. To explore how the gut microbiota helps the host adapt to high-altitude environments, we analyzed the differences in diversity and function of the gut microbiota between high- and low-altitude regions through full-length 16S rRNA sequencing. Our results show that high-altitude regions have a lower abundance of Fructobacillus and Saccharibacter compared to low-altitude regions. Additionally, some individuals in low-altitude regions were invaded by opportunistic pathogens. The gut microbiota in high-altitude regions has a greater number of pathways involved in “Protein digestion and absorption” and “Biosynthesis of amino acids,” while fewer carbohydrate pathways are involved in “digestion and absorption” and “Salmonella infection.” Our finding suggests that plateau hosts typically reduce energy metabolism and enhance immunity in response to adverse environments. Correspondingly, the gut microbiota also makes changes, such as reducing carbohydrate degradation and increasing protein utilization in response to the host. Additionally, the gut microbiota regulates their abundance and function to help the host adapt to adverse high-altitude environments. Frontiers Media S.A. 2023-08-02 /pmc/articles/PMC10433375/ /pubmed/37601385 http://dx.doi.org/10.3389/fmicb.2023.1218560 Text en Copyright © 2023 Zhang, Guo, Zhuang, Liu, Xia, Zhang, Yang, Zeng, Wu, Huang and Li. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Microbiology
Zhang, Zhengyi
Guo, Yulong
Zhuang, Mingsheng
Liu, Fugang
Xia, Zhongyan
Zhang, Zhihao
Yang, Fan
Zeng, Huayan
Wu, Yueguo
Huang, Jiaxing
Li, Jilian
Potential role of the gut microbiota of bumblebee Bombus pyrosoma in adaptation to high-altitude habitats
title Potential role of the gut microbiota of bumblebee Bombus pyrosoma in adaptation to high-altitude habitats
title_full Potential role of the gut microbiota of bumblebee Bombus pyrosoma in adaptation to high-altitude habitats
title_fullStr Potential role of the gut microbiota of bumblebee Bombus pyrosoma in adaptation to high-altitude habitats
title_full_unstemmed Potential role of the gut microbiota of bumblebee Bombus pyrosoma in adaptation to high-altitude habitats
title_short Potential role of the gut microbiota of bumblebee Bombus pyrosoma in adaptation to high-altitude habitats
title_sort potential role of the gut microbiota of bumblebee bombus pyrosoma in adaptation to high-altitude habitats
topic Microbiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10433375/
https://www.ncbi.nlm.nih.gov/pubmed/37601385
http://dx.doi.org/10.3389/fmicb.2023.1218560
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