Computational Exploration of Potential CFTR Binding Sites for Type I Corrector Drugs

[Image: see text] Cystic fibrosis (CF) is a recessive genetic disease that is caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) protein. The recent development of a class of drugs called “correctors”, which repair the structure and function of mutant CFTR, has gre...

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Detalles Bibliográficos
Autores principales: Lester, Anna, Sandman, Madeline, Herring, Caitlin, Girard, Christian, Dixon, Brandon, Ramsdell, Havanna, Reber, Callista, Poulos, Jack, Mitchell, Alexis, Spinney, Allison, Henager, Marissa E., Evans, Claudia N., Turlington, Mark, Johnson, Quentin R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10433520/
https://www.ncbi.nlm.nih.gov/pubmed/37437308
http://dx.doi.org/10.1021/acs.biochem.3c00165

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