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Spontaneous Formation of Ultrasmall Unilamellar Vesicles in Mixtures of an Amphiphilic Drug and a Phospholipid

[Image: see text] We have observed ultrasmall unilamellar vesicles, with diameters of less than 20 nm, in mixtures of the tricyclic antidepressant drug amitriptyline hydrochloride (AMT) and the unsaturated zwitterionic phospholipid 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) in physiological sal...

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Detalles Bibliográficos
Autores principales:	Forooqi Motlaq, Vahid, Gedda, Lars, Edwards, Katarina, Doutch, James, Bergström, L. Magnus
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2023
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10433524/ https://www.ncbi.nlm.nih.gov/pubmed/37530182 http://dx.doi.org/10.1021/acs.langmuir.3c01023

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