Determination of the Structure and Dynamics of the Fuzzy Coat of an Amyloid Fibril of IAPP Using Cryo-Electron Microscopy

[Image: see text] In recent years, major advances in cryo-electron microscopy (cryo-EM) have enabled the routine determination of complex biomolecular structures at atomistic resolution. An open challenge for this approach, however, concerns large systems that exhibit continuous dynamics. To address...

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Detalles Bibliográficos
Autores principales: Faidon Brotzakis, Z., Löhr, Thomas, Truong, Steven, Hoff, Samuel, Bonomi, Massimiliano, Vendruscolo, Michele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10433526/
https://www.ncbi.nlm.nih.gov/pubmed/37477459
http://dx.doi.org/10.1021/acs.biochem.3c00010

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