Sickle Cell Disease Treatment with Arginine Therapy (STArT): study protocol for a phase 3 randomized controlled trial

BACKGROUND: Despite substantial illness burden and healthcare utilization conferred by pain from vaso-occlusive episodes (VOE) in children with sickle cell disease (SCD), disease-modifying therapies to effectively treat SCD-VOE are lacking. The aim of the Sickle Cell Disease Treatment with Arginine...

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Detalles Bibliográficos
Autores principales: Rees, Chris A., Brousseau, David C., Cohen, Daniel M., Villella, Anthony, Dampier, Carlton, Brown, Kathleen, Campbell, Andrew, Chumpitazi, Corrie E., Airewele, Gladstone, Chang, Todd, Denton, Christopher, Ellison, Angela, Thompson, Alexis, Ahmad, Fahd, Bakshi, Nitya, Coleman, Keli D., Leibovich, Sara, Leake, Deborah, Hatabah, Dunia, Wilkinson, Hagar, Robinson, Michelle, Casper, T. Charles, Vichinsky, Elliott, Morris, Claudia R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10433602/
https://www.ncbi.nlm.nih.gov/pubmed/37587492
http://dx.doi.org/10.1186/s13063-023-07538-z

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