Microglial senescence contributes to female-biased neuroinflammation in the aging mouse hippocampus: implications for Alzheimer’s disease

BACKGROUND: Microglia, the brain’s principal immune cells, have been implicated in the pathogenesis of Alzheimer’s disease (AD), a condition shown to affect more females than males. Although sex differences in microglial function and transcriptomic programming have been described across development...

Descripción completa

Detalles Bibliográficos
Autores principales: Ocañas, Sarah R., Pham, Kevin D., Cox, Jillian E. J., Keck, Alex W., Ko, Sunghwan, Ampadu, Felix A., Porter, Hunter L., Ansere, Victor A., Kulpa, Adam, Kellogg, Collyn M., Machalinski, Adeline H., Thomas, Manu A., Wright, Zsabre, Chucair-Elliott, Ana J., Freeman, Willard M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10433617/
https://www.ncbi.nlm.nih.gov/pubmed/37587511
http://dx.doi.org/10.1186/s12974-023-02870-2

Ejemplares similares

Ejemplares similares