The effects of environmental factors associated with childhood urbanicity on brain structure and cognition

Urbanization is a trend lasting for more than one century worldwide. Four hundred ninety male and female adult Chinese Han participants with different urban and rural childhoods were included in this study. Early-life urban environment was found benefit for total grey matter volume (GMV), dorsolater...

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Autores principales: Zhang, Xiao, Yan, Hao, Yu, Hao, Zhang, Yuyanan, Tan, Hao Yang, Zhang, Dai, Yue, Weihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10433654/
https://www.ncbi.nlm.nih.gov/pubmed/37592210
http://dx.doi.org/10.1186/s12888-023-05066-3
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author Zhang, Xiao
Yan, Hao
Yu, Hao
Zhang, Yuyanan
Tan, Hao Yang
Zhang, Dai
Yue, Weihua
author_facet Zhang, Xiao
Yan, Hao
Yu, Hao
Zhang, Yuyanan
Tan, Hao Yang
Zhang, Dai
Yue, Weihua
author_sort Zhang, Xiao
collection PubMed
description Urbanization is a trend lasting for more than one century worldwide. Four hundred ninety male and female adult Chinese Han participants with different urban and rural childhoods were included in this study. Early-life urban environment was found benefit for total grey matter volume (GMV), dorsolateral prefrontal cortex (DLPFC) GMV, temporal pole (TP) GMV and cognition function, and negatively correlated with medial prefrontal cortex (MPFC) GMV. Regression analysis showed that maternal education was a protective factor for total and DLPFC GMVs, while having siblings was better for MPFC GMV. Total, DLPFC and TP GMVs acts mediation effects between childhood urbanicity and different cognitive domains. These findings may suggest some pros and cons on brain structure associated with childhood urbanicity and related environmental factors. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12888-023-05066-3.
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spelling pubmed-104336542023-08-18 The effects of environmental factors associated with childhood urbanicity on brain structure and cognition Zhang, Xiao Yan, Hao Yu, Hao Zhang, Yuyanan Tan, Hao Yang Zhang, Dai Yue, Weihua BMC Psychiatry Research Urbanization is a trend lasting for more than one century worldwide. Four hundred ninety male and female adult Chinese Han participants with different urban and rural childhoods were included in this study. Early-life urban environment was found benefit for total grey matter volume (GMV), dorsolateral prefrontal cortex (DLPFC) GMV, temporal pole (TP) GMV and cognition function, and negatively correlated with medial prefrontal cortex (MPFC) GMV. Regression analysis showed that maternal education was a protective factor for total and DLPFC GMVs, while having siblings was better for MPFC GMV. Total, DLPFC and TP GMVs acts mediation effects between childhood urbanicity and different cognitive domains. These findings may suggest some pros and cons on brain structure associated with childhood urbanicity and related environmental factors. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12888-023-05066-3. BioMed Central 2023-08-17 /pmc/articles/PMC10433654/ /pubmed/37592210 http://dx.doi.org/10.1186/s12888-023-05066-3 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Zhang, Xiao
Yan, Hao
Yu, Hao
Zhang, Yuyanan
Tan, Hao Yang
Zhang, Dai
Yue, Weihua
The effects of environmental factors associated with childhood urbanicity on brain structure and cognition
title The effects of environmental factors associated with childhood urbanicity on brain structure and cognition
title_full The effects of environmental factors associated with childhood urbanicity on brain structure and cognition
title_fullStr The effects of environmental factors associated with childhood urbanicity on brain structure and cognition
title_full_unstemmed The effects of environmental factors associated with childhood urbanicity on brain structure and cognition
title_short The effects of environmental factors associated with childhood urbanicity on brain structure and cognition
title_sort effects of environmental factors associated with childhood urbanicity on brain structure and cognition
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10433654/
https://www.ncbi.nlm.nih.gov/pubmed/37592210
http://dx.doi.org/10.1186/s12888-023-05066-3
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