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Silencing of GRHL2 induces epithelial‑to‑mesenchymal transition in lung cancer cell lines with different effects on proliferation and clonogenic growth

Grainyhead-like 2 (GRHL2) is a transcription factor that suppresses epithelial-to-mesenchymal transition (EMT). It has been previously shown that GRHL2 can confer both oncogenic and tumor-suppressive roles in human cancers, including breast, pancreatic and colorectal cancers. However, its role in lu...

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Detalles Bibliográficos
Autores principales: Kawabe, Nozomi, Matsuoka, Kohei, Komeda, Kazuki, Muraki, Nao, Takaba, Miho, Togami, Yasuha, Ito, Yumeno, Yamada, Mizuki, Sunaga, Noriaki, Girard, Luc, Minna, John D., Cai, Ling, Xie, Yang, Tanaka, Ichidai, Morise, Masahiro, Sato, Mitsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10433723/
https://www.ncbi.nlm.nih.gov/pubmed/37600329
http://dx.doi.org/10.3892/ol.2023.13977

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