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Clinical Characteristics and Treatment Outcomes of Mycobacterium fortuitum Pulmonary Disease
We evaluated the clinical characteristics and treatment outcomes of 35 patients diagnosed with Mycobacterium fortuitum-pulmonary disease (M. fortuitum-PD). Prior to treatment, all isolates were sensitive to amikacin and 73% and 90% were sensitive to imipenem and moxifloxacin, respectively. Approxima...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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American Society for Microbiology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10433795/ https://www.ncbi.nlm.nih.gov/pubmed/37428038 http://dx.doi.org/10.1128/spectrum.02051-23 |
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author | Kim, Sae Rom Yu, Jin Young Kim, Su-Young Kim, Dae Hun Jhun, Byung Woo |
author_facet | Kim, Sae Rom Yu, Jin Young Kim, Su-Young Kim, Dae Hun Jhun, Byung Woo |
author_sort | Kim, Sae Rom |
collection | PubMed |
description | We evaluated the clinical characteristics and treatment outcomes of 35 patients diagnosed with Mycobacterium fortuitum-pulmonary disease (M. fortuitum-PD). Prior to treatment, all isolates were sensitive to amikacin and 73% and 90% were sensitive to imipenem and moxifloxacin, respectively. Approximately two-thirds of the patients (24 of 35) remained stable without antibiotic treatment. Of 11 patients requiring antibiotic treatment, the majority (81%, 9 of 11) achieved a microbiological cure with susceptible antibiotics. IMPORTANCE Mycobacterium fortuitum (M. fortuitum) is a rapidly growing mycobacterium that causes M. fortuitum-pulmonary disease (PD). It is common among individuals with preexisting lung conditions. Limited data exist regarding treatment and prognosis. Our study examined patients with M. fortuitum-PD. Two-thirds of them remained stable without antibiotics. Among those requiring treatment, 81% achieved a microbiological cure with suitable antibiotics. In many cases, M. fortuitum-PD follows a stable course without antibiotics, and when necessary, a favorable treatment response can be achieved with the appropriate antibiotics. |
format | Online Article Text |
id | pubmed-10433795 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | American Society for Microbiology |
record_format | MEDLINE/PubMed |
spelling | pubmed-104337952023-08-18 Clinical Characteristics and Treatment Outcomes of Mycobacterium fortuitum Pulmonary Disease Kim, Sae Rom Yu, Jin Young Kim, Su-Young Kim, Dae Hun Jhun, Byung Woo Microbiol Spectr Observation We evaluated the clinical characteristics and treatment outcomes of 35 patients diagnosed with Mycobacterium fortuitum-pulmonary disease (M. fortuitum-PD). Prior to treatment, all isolates were sensitive to amikacin and 73% and 90% were sensitive to imipenem and moxifloxacin, respectively. Approximately two-thirds of the patients (24 of 35) remained stable without antibiotic treatment. Of 11 patients requiring antibiotic treatment, the majority (81%, 9 of 11) achieved a microbiological cure with susceptible antibiotics. IMPORTANCE Mycobacterium fortuitum (M. fortuitum) is a rapidly growing mycobacterium that causes M. fortuitum-pulmonary disease (PD). It is common among individuals with preexisting lung conditions. Limited data exist regarding treatment and prognosis. Our study examined patients with M. fortuitum-PD. Two-thirds of them remained stable without antibiotics. Among those requiring treatment, 81% achieved a microbiological cure with suitable antibiotics. In many cases, M. fortuitum-PD follows a stable course without antibiotics, and when necessary, a favorable treatment response can be achieved with the appropriate antibiotics. American Society for Microbiology 2023-07-10 /pmc/articles/PMC10433795/ /pubmed/37428038 http://dx.doi.org/10.1128/spectrum.02051-23 Text en https://doi.org/10.1128/AuthorWarrantyLicense.v1This is a work of the U.S. Government and is not subject to copyright protection in the United States. Foreign copyrights may apply. |
spellingShingle | Observation Kim, Sae Rom Yu, Jin Young Kim, Su-Young Kim, Dae Hun Jhun, Byung Woo Clinical Characteristics and Treatment Outcomes of Mycobacterium fortuitum Pulmonary Disease |
title | Clinical Characteristics and Treatment Outcomes of Mycobacterium fortuitum Pulmonary Disease |
title_full | Clinical Characteristics and Treatment Outcomes of Mycobacterium fortuitum Pulmonary Disease |
title_fullStr | Clinical Characteristics and Treatment Outcomes of Mycobacterium fortuitum Pulmonary Disease |
title_full_unstemmed | Clinical Characteristics and Treatment Outcomes of Mycobacterium fortuitum Pulmonary Disease |
title_short | Clinical Characteristics and Treatment Outcomes of Mycobacterium fortuitum Pulmonary Disease |
title_sort | clinical characteristics and treatment outcomes of mycobacterium fortuitum pulmonary disease |
topic | Observation |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10433795/ https://www.ncbi.nlm.nih.gov/pubmed/37428038 http://dx.doi.org/10.1128/spectrum.02051-23 |
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