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Host Factor Nucleophosmin 1 (NPM1/B23) Exerts Antiviral Effects against Chikungunya Virus by Its Interaction with Viral Nonstructural Protein 3

Chikungunya virus (CHIKV) hijacks host cell machinery to support its replication. Nucleophosmin 1 (NPM1/B23), a nucleolar phosphoprotein, is one of the host proteins known to restrict CHIKV infection; however, the mechanistic details of the antiviral role of NPM1 are not elucidated. It was seen in o...

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Detalles Bibliográficos
Autores principales: Pradeep, Parvanendhu, Sivakumar, Krishnankutty Chandrika, Sreekumar, Easwaran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10433958/
https://www.ncbi.nlm.nih.gov/pubmed/37409962
http://dx.doi.org/10.1128/spectrum.05371-22

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