Growth Transformation of B Cells by Epstein-Barr Virus Requires IMPDH2 Induction and Nucleolar Hypertrophy

The in vitro growth transformation of primary B cells by Epstein-Barr virus (EBV) is the initial step in the development of posttransplant lymphoproliferative disorder (PTLD). We performed electron microscopic analysis and immunostaining of primary B cells infected with wild-type EBV. Interestingly,...

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Detalles Bibliográficos
Autores principales: Sugimoto, Atsuko, Watanabe, Takahiro, Matsuoka, Kazuhiro, Okuno, Yusuke, Yanagi, Yusuke, Narita, Yohei, Mabuchi, Seiyo, Nobusue, Hiroyuki, Sugihara, Eiji, Hirayama, Masaya, Ide, Tomihiko, Onouchi, Takanori, Sato, Yoshitaka, Kanda, Teru, Saya, Hideyuki, Iwatani, Yasumasa, Kimura, Hiroshi, Murata, Takayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10433962/
https://www.ncbi.nlm.nih.gov/pubmed/37409959
http://dx.doi.org/10.1128/spectrum.00440-23

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