Characterization of In Vitro Resistance to Linezolid in Mycobacterium abscessus

Single-step selection of Mycobacterium abscessus mutants resistant to linezolid yielded high-level resistance at a low frequency that was associated with mutations in 23S rRNA or the ribosomal protein L3. Surprisingly, linezolid-resistant rRNA mutations conferred cross-resistance to several unrelate...

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Detalles Bibliográficos
Autores principales: Negatu, Dereje A., Aragaw, Wassihun Wedajo, Dartois, Véronique, Dick, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10434030/
https://www.ncbi.nlm.nih.gov/pubmed/37458588
http://dx.doi.org/10.1128/spectrum.02199-23

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10434030/
https://www.ncbi.nlm.nih.gov/pubmed/37458588
http://dx.doi.org/10.1128/spectrum.02199-23

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