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Characterization of In Vitro Resistance to Linezolid in Mycobacterium abscessus
Single-step selection of Mycobacterium abscessus mutants resistant to linezolid yielded high-level resistance at a low frequency that was associated with mutations in 23S rRNA or the ribosomal protein L3. Surprisingly, linezolid-resistant rRNA mutations conferred cross-resistance to several unrelate...
Autores principales: | Negatu, Dereje A., Aragaw, Wassihun Wedajo, Dartois, Véronique, Dick, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10434030/ https://www.ncbi.nlm.nih.gov/pubmed/37458588 http://dx.doi.org/10.1128/spectrum.02199-23 |
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