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Determining the Time of Booster Dose Based on the Half-Life and Neutralization Titers against SARS-CoV-2 Variants of Concern in Fully Vaccinated Individuals

Although mRNA-based COVID-19 vaccines reduce the risk of severe disease, hospitalization and death, vaccine effectiveness (VE) against infection and disease from variants of concern (VOC) wanes over time. Neutralizing antibodies (NAb) are surrogates of protection and are enhanced by a booster dose,...

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Detalles Bibliográficos
Autores principales: Dai, Yu-Ching, Lin, Yen-Chia, Ching, Lauren L., Tsai, Jih-Jin, Ishikawa, Kyle, Tsai, Wen-Yang, Chen, John J., Nerurkar, Vivek R., Wang, Wei-Kung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10434144/
https://www.ncbi.nlm.nih.gov/pubmed/37428104
http://dx.doi.org/10.1128/spectrum.04081-22