The Disorazole Z Family of Highly Potent Anticancer Natural Products from Sorangium cellulosum: Structure, Bioactivity, Biosynthesis, and Heterologous Expression

Myxobacteria serve as a treasure trove of secondary metabolites. During our ongoing search for bioactive natural products, a novel subclass of disorazoles termed disorazole Z was discovered. Ten disorazole Z family members were purified from a large-scale fermentation of the myxobacterium Sorangium...

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Detalles Bibliográficos
Autores principales: Gao, Yunsheng, Birkelbach, Joy, Fu, Chengzhang, Herrmann, Jennifer, Irschik, Herbert, Morgenstern, Bernd, Hirschfelder, Kerstin, Li, Ruijuan, Zhang, Youming, Jansen, Rolf, Müller, Rolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10434194/
https://www.ncbi.nlm.nih.gov/pubmed/37318329
http://dx.doi.org/10.1128/spectrum.00730-23

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10434194/
https://www.ncbi.nlm.nih.gov/pubmed/37318329
http://dx.doi.org/10.1128/spectrum.00730-23

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