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The Disorazole Z Family of Highly Potent Anticancer Natural Products from Sorangium cellulosum: Structure, Bioactivity, Biosynthesis, and Heterologous Expression
Myxobacteria serve as a treasure trove of secondary metabolites. During our ongoing search for bioactive natural products, a novel subclass of disorazoles termed disorazole Z was discovered. Ten disorazole Z family members were purified from a large-scale fermentation of the myxobacterium Sorangium...
Autores principales: | Gao, Yunsheng, Birkelbach, Joy, Fu, Chengzhang, Herrmann, Jennifer, Irschik, Herbert, Morgenstern, Bernd, Hirschfelder, Kerstin, Li, Ruijuan, Zhang, Youming, Jansen, Rolf, Müller, Rolf |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10434194/ https://www.ncbi.nlm.nih.gov/pubmed/37318329 http://dx.doi.org/10.1128/spectrum.00730-23 |
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