ROS induced lipid peroxidation and their role in ferroptosis

Reactive oxygen species (ROS) play a crucial part in the process of cell death, including apoptosis, autophagy, and ferroptosis. ROS involves in the oxidation of lipids and generate 4-hydroxynonenal and other compounds associated with it. Ferroptosis may be facilitated by lipid peroxidation of phosp...

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Autores principales: Endale, Hiwot Tezera, Tesfaye, Winta, Mengstie, Tiget Ayelgn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10434548/
https://www.ncbi.nlm.nih.gov/pubmed/37601095
http://dx.doi.org/10.3389/fcell.2023.1226044
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author Endale, Hiwot Tezera
Tesfaye, Winta
Mengstie, Tiget Ayelgn
author_facet Endale, Hiwot Tezera
Tesfaye, Winta
Mengstie, Tiget Ayelgn
author_sort Endale, Hiwot Tezera
collection PubMed
description Reactive oxygen species (ROS) play a crucial part in the process of cell death, including apoptosis, autophagy, and ferroptosis. ROS involves in the oxidation of lipids and generate 4-hydroxynonenal and other compounds associated with it. Ferroptosis may be facilitated by lipid peroxidation of phospholipid bilayers. In order to offer novel ideas and directions for the investigation of disorders connected to these processes, we evaluate the function of ROS in lipid peroxidation which ultimately leads to ferroptosis as well as proposed crosstalk mechanisms between ferroptosis and other types programmed cell death.
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spelling pubmed-104345482023-08-18 ROS induced lipid peroxidation and their role in ferroptosis Endale, Hiwot Tezera Tesfaye, Winta Mengstie, Tiget Ayelgn Front Cell Dev Biol Cell and Developmental Biology Reactive oxygen species (ROS) play a crucial part in the process of cell death, including apoptosis, autophagy, and ferroptosis. ROS involves in the oxidation of lipids and generate 4-hydroxynonenal and other compounds associated with it. Ferroptosis may be facilitated by lipid peroxidation of phospholipid bilayers. In order to offer novel ideas and directions for the investigation of disorders connected to these processes, we evaluate the function of ROS in lipid peroxidation which ultimately leads to ferroptosis as well as proposed crosstalk mechanisms between ferroptosis and other types programmed cell death. Frontiers Media S.A. 2023-08-01 /pmc/articles/PMC10434548/ /pubmed/37601095 http://dx.doi.org/10.3389/fcell.2023.1226044 Text en Copyright © 2023 Endale, Tesfaye and Mengstie. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Cell and Developmental Biology
Endale, Hiwot Tezera
Tesfaye, Winta
Mengstie, Tiget Ayelgn
ROS induced lipid peroxidation and their role in ferroptosis
title ROS induced lipid peroxidation and their role in ferroptosis
title_full ROS induced lipid peroxidation and their role in ferroptosis
title_fullStr ROS induced lipid peroxidation and their role in ferroptosis
title_full_unstemmed ROS induced lipid peroxidation and their role in ferroptosis
title_short ROS induced lipid peroxidation and their role in ferroptosis
title_sort ros induced lipid peroxidation and their role in ferroptosis
topic Cell and Developmental Biology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10434548/
https://www.ncbi.nlm.nih.gov/pubmed/37601095
http://dx.doi.org/10.3389/fcell.2023.1226044
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