Noncoding de novo mutations contribute to autism via long-range chromatin interactions

INTRODUCTION: Three-dimensional chromatin interactions regulate gene expressions. The significance of de novo mutations (DNMs) in chromatin interactions remains poorly understood for autism spectrum disorder (ASD). OBJECTIVES: To investigate the genomic architecture of ASD in terms of non-coding de...

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Detalles Bibliográficos
Autores principales: Kim, I. B., Choi, J., Park, J. E., Lee, J.-C., Jung, S.-B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2023
Materias:
Abstract
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10434619/
http://dx.doi.org/10.1192/j.eurpsy.2023.764

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