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Magnitude and associated factors of mortality among patients admitted with COVID-19 in Addis Ababa, Ethiopia

The COVID-19 pandemic continues to grow around the world and has caused enormous mortality and morbidity. The severity and mortality of coronavirus disease are associated with various comorbidities. The infection fatality rate was reported to be inconsistent with different studies. Therefore, the ai...

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Autores principales: Getahun, Genanew Kassie, Dinku, Amare, Jara, Dube, Shitemaw, Tewodros, Negash, Zelalem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10434868/
https://www.ncbi.nlm.nih.gov/pubmed/37590230
http://dx.doi.org/10.1371/journal.pgph.0000420
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author Getahun, Genanew Kassie
Dinku, Amare
Jara, Dube
Shitemaw, Tewodros
Negash, Zelalem
author_facet Getahun, Genanew Kassie
Dinku, Amare
Jara, Dube
Shitemaw, Tewodros
Negash, Zelalem
author_sort Getahun, Genanew Kassie
collection PubMed
description The COVID-19 pandemic continues to grow around the world and has caused enormous mortality and morbidity. The severity and mortality of coronavirus disease are associated with various comorbidities. The infection fatality rate was reported to be inconsistent with different studies. Therefore, the aim of this study was to assess the magnitude and factors associated with mortality among patients admitted to Eka Kotebe General Hospital, Addis Ababa, Ethiopia. An institutional-based cross-sectional study was conducted at Eka Kotebe General Hospital among patients who were admitted for COVID-19 from January 15, 2021, to June 30, 2021. A total of 393 records of patients were selected by simple random sampling. Data was extracted from compiled data forms where available information was already tabulated. Data was entered and analyzed using SPSS version 25. The determinant factors associated with mortality among COVID-19 patients were identified using bivariate and multivariable logistic regression analysis. A statistical association was declared with multivariable logistic regression using a 95% confidence interval and a P-value of less than 0.05. The proportion of COVID-19 mortality among patients admitted to Eka Kotebe General Hospital was 8.1% (95% CI (5.4–10.8%)). Age >50 years [AOR = 7.91; 95% CI (2.34–25.70)], being male [AOR = 2.09; 95% CI (1.20–3.65)], having diabetes mellitus [AOR = 2.64; 95% CI (1.30–5.35)], having hypertension [AOR = 2.67; 95% CI (1.22–5.88)] and having chronic kidney disease [AOR = 12.04; 95% CI (4.03–14.22)] were determinant factors of COVID-19 mortality. The current study findings revealed that COVID-19 mortality was high among hospitalized COVID-19 patients. Furthermore, age, gender, diabetes mellitus, hypertension, and chronic kidney disease were discovered to be independent predictors of COVID-19 mortality. Therefore, older COVID-19 patients and those with established comorbidities such as hypertension, diabetes, and end-stage renal disease should receive comprehensive preventative efforts, including vaccination.
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spelling pubmed-104348682023-08-18 Magnitude and associated factors of mortality among patients admitted with COVID-19 in Addis Ababa, Ethiopia Getahun, Genanew Kassie Dinku, Amare Jara, Dube Shitemaw, Tewodros Negash, Zelalem PLOS Glob Public Health Research Article The COVID-19 pandemic continues to grow around the world and has caused enormous mortality and morbidity. The severity and mortality of coronavirus disease are associated with various comorbidities. The infection fatality rate was reported to be inconsistent with different studies. Therefore, the aim of this study was to assess the magnitude and factors associated with mortality among patients admitted to Eka Kotebe General Hospital, Addis Ababa, Ethiopia. An institutional-based cross-sectional study was conducted at Eka Kotebe General Hospital among patients who were admitted for COVID-19 from January 15, 2021, to June 30, 2021. A total of 393 records of patients were selected by simple random sampling. Data was extracted from compiled data forms where available information was already tabulated. Data was entered and analyzed using SPSS version 25. The determinant factors associated with mortality among COVID-19 patients were identified using bivariate and multivariable logistic regression analysis. A statistical association was declared with multivariable logistic regression using a 95% confidence interval and a P-value of less than 0.05. The proportion of COVID-19 mortality among patients admitted to Eka Kotebe General Hospital was 8.1% (95% CI (5.4–10.8%)). Age >50 years [AOR = 7.91; 95% CI (2.34–25.70)], being male [AOR = 2.09; 95% CI (1.20–3.65)], having diabetes mellitus [AOR = 2.64; 95% CI (1.30–5.35)], having hypertension [AOR = 2.67; 95% CI (1.22–5.88)] and having chronic kidney disease [AOR = 12.04; 95% CI (4.03–14.22)] were determinant factors of COVID-19 mortality. The current study findings revealed that COVID-19 mortality was high among hospitalized COVID-19 patients. Furthermore, age, gender, diabetes mellitus, hypertension, and chronic kidney disease were discovered to be independent predictors of COVID-19 mortality. Therefore, older COVID-19 patients and those with established comorbidities such as hypertension, diabetes, and end-stage renal disease should receive comprehensive preventative efforts, including vaccination. Public Library of Science 2023-08-17 /pmc/articles/PMC10434868/ /pubmed/37590230 http://dx.doi.org/10.1371/journal.pgph.0000420 Text en © 2023 Getahun et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Getahun, Genanew Kassie
Dinku, Amare
Jara, Dube
Shitemaw, Tewodros
Negash, Zelalem
Magnitude and associated factors of mortality among patients admitted with COVID-19 in Addis Ababa, Ethiopia
title Magnitude and associated factors of mortality among patients admitted with COVID-19 in Addis Ababa, Ethiopia
title_full Magnitude and associated factors of mortality among patients admitted with COVID-19 in Addis Ababa, Ethiopia
title_fullStr Magnitude and associated factors of mortality among patients admitted with COVID-19 in Addis Ababa, Ethiopia
title_full_unstemmed Magnitude and associated factors of mortality among patients admitted with COVID-19 in Addis Ababa, Ethiopia
title_short Magnitude and associated factors of mortality among patients admitted with COVID-19 in Addis Ababa, Ethiopia
title_sort magnitude and associated factors of mortality among patients admitted with covid-19 in addis ababa, ethiopia
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10434868/
https://www.ncbi.nlm.nih.gov/pubmed/37590230
http://dx.doi.org/10.1371/journal.pgph.0000420
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