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Optogenetic manipulation of Gq- and Gi/o-coupled receptor signaling in neurons and heart muscle cells

G-protein-coupled receptors (GPCRs) transmit signals into cells depending on the G protein type. To analyze the functions of GPCR signaling, we assessed the effectiveness of animal G-protein-coupled bistable rhodopsins that can be controlled into active and inactive states by light application using...

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Detalles Bibliográficos
Autores principales: Hagio, Hanako, Koyama, Wataru, Hosaka, Shiori, Song, Aysenur Deniz, Narantsatsral, Janchiv, Matsuda, Koji, Sugihara, Tomohiro, Shimizu, Takashi, Koyanagi, Mitsumasa, Terakita, Akihisa, Hibi, Masahiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10435233/
https://www.ncbi.nlm.nih.gov/pubmed/37589544
http://dx.doi.org/10.7554/eLife.83974