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Cas phosphorylation regulates focal adhesion assembly

Integrin-mediated cell attachment rapidly induces tyrosine kinase signaling. Despite years of research, the role of this signaling in integrin activation and focal adhesion assembly is unclear. We provide evidence that the Src-family kinase (SFK) substrate Cas (Crk-associated substrate, p130Cas, BCA...

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Detalles Bibliográficos
Autores principales: Kumar, Saurav, Stainer, Amanda, Dubrulle, Julien, Simpkins, Christopher, Cooper, Jonathan A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10435235/
https://www.ncbi.nlm.nih.gov/pubmed/37489578
http://dx.doi.org/10.7554/eLife.90234

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