The Kruppel-like factor 4-signal transducer and activator of transcription 5A axis promotes pancreatic fibrosis in mice with caerulein-induced chronic pancreatitis

Pancreatic fibrosis (PF) is a hallmark of chronic pancreatitis (CP), but its molecular mechanism remains unclear. This study was conducted to explore the role of Kruppel-like factor 4 (KLF4) in PF in CP mice. The CP mouse model was established using caerulein. After KLF4 interference, pathological c...

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Detalles Bibliográficos
Autores principales: Wang, Xiaoxiang, Yu, Lan, Chen, Yao, Xiong, Xing, Ran, Hongmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Association for Laboratory Animal Science 2023
Materias:
Original
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10435357/
https://www.ncbi.nlm.nih.gov/pubmed/36948613
http://dx.doi.org/10.1538/expanim.22-0147

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