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Anti-tumor effect of avadomide in gemcitabine-resistant pancreatic ductal adenocarcinoma

PURPOSE: Although gemcitabine-based chemotherapy is most recommended for pancreatic ductal adenocarcinoma (PDAC), its effectiveness is limited because of drug resistance. Given thalidomide’s anti-tumor effects in solid tumors, we investigated the effect of avadomide, a novel thalidomide analog, on P...

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Detalles Bibliográficos
Autores principales: Nishi, Hidemi, Gotoh, Kunihito, Tomimaru, Yoshito, Kobayashi, Shogo, Sasaki, Kazuki, Iwagami, Yoshifumi, Yamada, Daisaku, Akita, Hirofumi, Asaoka, Tadafumi, Noda, Takehiro, Takahashi, Hidenori, Tanemura, Masahiro, Doki, Yuichiro, Eguchi, Hidetoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10435408/
https://www.ncbi.nlm.nih.gov/pubmed/37491611
http://dx.doi.org/10.1007/s00280-023-04531-w