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Developing multitarget coumarin based anti-breast cancer agents: synthesis and molecular modeling study
A new series of 7-substituted coumarin scaffolds containing a methyl ester moiety at the C(4)-position were synthesized and tested for their in vitro anti-proliferative activity against MCF-7 and MDA-MB-231 breast cancer cell lines using Doxorubicin (DOX) as reference. Compounds 2 and 8 showed notic...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10435442/ https://www.ncbi.nlm.nih.gov/pubmed/37591917 http://dx.doi.org/10.1038/s41598-023-40232-3 |