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RORγt-Raftlin1 complex regulates the pathogenicity of Th17 cells and colonic inflammation
Th17 cells that produce Interleukin IL-17 are pathogenic in many human diseases, including inflammatory bowel disease, but are, paradoxically, essential for maintaining the integrity of the intestinal barrier in a non-inflammatory state. However, the intracellular mechanisms that regulate distinct t...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10435467/ https://www.ncbi.nlm.nih.gov/pubmed/37591835 http://dx.doi.org/10.1038/s41467-023-40622-1 |