RORγt-Raftlin1 complex regulates the pathogenicity of Th17 cells and colonic inflammation

Th17 cells that produce Interleukin IL-17 are pathogenic in many human diseases, including inflammatory bowel disease, but are, paradoxically, essential for maintaining the integrity of the intestinal barrier in a non-inflammatory state. However, the intracellular mechanisms that regulate distinct t...

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Detalles Bibliográficos
Autores principales: Singh, Amir Kumar, Kumar, Ritesh, Yin, Jianyi, Brooks II, John F., Kathania, Mahesh, Mukherjee, Sandip, Kumar, Jitendra, Conlon, Kevin P., Basrur, Venkatesha, Chen, Zhe, Han, Xianlin, Hooper, Lora V., Burstein, Ezra, Venuprasad, K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10435467/
https://www.ncbi.nlm.nih.gov/pubmed/37591835
http://dx.doi.org/10.1038/s41467-023-40622-1

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